Mozak will experience a brief downtime from approximately 11:00am to 11:30am (Pacific Time Zone) on Monday, May 22nd Tuesday, May 23rd. This short little break will allow us to make some behind the scenes changes that will help us deliver new features faster and easier. We apologize in advance for the inconvenience.
Over the next week or two, we are hoping to roll out some new features. Among these are undo/redo, the ability to hide the consensus, and a cool feature called auto-depth. Auto-depth will occur automatically when a player places a node in Connect-the-Dots mode. It will search a few of the surrounding layers and ensure the node is placed on the layer where the neuronal signal is the brightest. This should help ensure precision placement and increased accuracy.
What features are most important to you? Is there a feature listed above that you are excited to see implemented? Are there other features or tools you think would make Mozak better? Pop over to the forum thread and have your voice be heard!
Yesterday, KOMO News featured an article about Mozak and one of our local players!
"Since Mozak launched in November, developers at the UW say about 200 people a day have been playing Mozak, which has allowed Allen Institute neuroscientists to reconstruct neurons 3.6 times faster than previous methods."
Huge thanks to both KOMO News and our local player, Marilyn, who was featured!
You can read the full article here.
Here is the latest round of feedback from our friendly, neighborhood neuroscientist ‘alexh’. On V1-19 you guys helped reconstruct the axon, an area the previous gold standard hadn’t touched. Nicely done! There are also some areas for improvement, so keep reading to hear what ‘alexh’ had to say about each reconstruction:
Gold Standard: 78983px
Consensus: 41360px (52%)
I must have pulled this one too soon. There is a lot of axon that had yet to be captured, and from past experience, I think more of it could have been capture if I had directed with more comments. On the plus side, this consensus would have been a great starting point for us because it has almost zero false positive signal. Please note that the MIP (maximum intensity projection) does not show much axon because the signal-to-noise ratio is too low. This is an example of one of the harder axons to reconstruct for us, so it is not surprising that it was challenging.
Gold Standard: 27202px
Consensus: 45343px (166%)
In this case, our gold standard was dendrite-only, and the dendrite portion of the consensus is perfect. The axon that the players traced looks very good, and we may end up using it to add the axon to our existing reconstruction! Thanks, players! Well done!
Gold Standard: 24661px
Consensus: 54694px (220%)
In this case, the players traced the neuron nearly perfectly, missing only one dendrite tip, but then continued to trace a lot of false positive signal present in the image. One factor that contributed is that this human tissue has a different appearance than the mouse tissue that the players are used to tracing. In this case, the quality that would indicate that the signal is false is that it is very thick, very diffuse and does not connect to the main structure. I’m guessing that much of the false signal is vasculature in this case.
All in all, you've got a lot to be proud of, players! Keep up the exceptional work and we'll let you know when the next round of feedback comes rolling in.