Allen Institute for Brain Science scientist “Alexh” compiled some thoughts on our recent puzzle, and we wanted to share them with you.
“Late last week, I did a comparison between the latest cell and the gold standard. Overall, I was very encouraged by the result. For the dendrites particularly, there was good agreement between traces.
Almost every segment of dendrite was represented in the consensus, and I even found a place where tracers captured a dendritic branch that we missed in the gold standard (A)! There were also places where the community mistakenly extended a branch (B), or created a surprisingly plausible looking structure out of noise (C). Additionally, there are very short segments (D) that are also false positives. The false positives shown at B, C and D, are all a product of artifactual signal near the surface of the slice. We have learned it is common that the first few planes near the surface of the tissue will have a lot of junk that looks like signal so we are extra discerning when tracing in that zone.”
Good work, everyone! We can’t wait to see what you accomplish next!
This new puzzle is a fresh mouse neuron from the primary visual cortex. As always, thank you to our scientists at the Allen Institute for Brain Science for providing this challenge. Get started on it now!
Hi everybody! Just a heads up to remind everyone that here at Mozak headquarters (the University of Washington), we are officially on holiday this upcoming Thursday and Friday, November 24 and 25. During this time we will be monitoring Mozak and responding to emergency issues, but otherwise you can expect likely delays to responses for posted issues until Monday morning (Pacific time). Rest assured when we are back from the weekend, the entire team will be ready to tackle all the great bugs and suggestions you have been posting for us in our community forums. For those of you also celebrating this weekend, we wish you safe travels where appropriate - and of course, a fantastic weekend to all.
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